Congenital malformations & Birth Complications

A congenital disease, otherwise called as congenital disorder deformity, birth imperfection, or irregularity, is a condition existing at or before birth without any cause these disorders, which are described by structural deformities are termed as “Congenital Anomalies". Birth defects vary widely in signs and symptoms, mainly the substance which cause’s birth defect is known as teratogen. Few disorders can be detected before through perinatal Screening (diagnosis)

Birth defects might be the result of environmental or genetic factors. This incorporates errors of contamination, Morphogenesis, epigenetic adjustments on a parental germ line, or a chromosomal abnormality. The result of the disorder will rely upon complex interactions between the pre-natal shortfall and the post-natal condition.  Animal studies have demonstrated that paternal exposures before and amid pregnancy result in increased risk of certain birth defects and tumors.

 

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